advanced prostate cancer treatment news Author: ertweryt
French
advanced prostate cancer treatment news Author: ertweryt
French scientists tested with mice and found that the treatment of diabetes and epilepsy with combined the two drugs for the treatment of prostate cancer, can inhibit tumor growth and cancer cell proliferation, thereby treating prostate cancer has opened up new avenues.
The advanced prostate cancer treatment news is as belows:
The study is completed by the French National Health and Medical Research scientists, the results was published in “Molecular and Cell Biology” magazine in October.
The main objective of this innovative therapy is to PPARgamma protein, this protein is a nuclear hormone receptor, can regulate gene expression of extracellular signals.
The researchers found that this protein has been a particular ligand activated, can inhibit the reproduction of malignant cancer cells. In addition, another group of molecules, namely, histone deacetylase inhibitors, PPARgamma protein can also activate this function, inhibit cancer cell proliferation.
On this basis, the researchers found there will be a function to mimic the ligand molecules,with a histone deacetylase inhibitors in mice experiments. The results showed that the two drugs used simultaneously can not only effectively control the growth of tumor in the lesion area, but also can inhibit the proliferation of cancer cells.
The researchers said they have already used two drugs in treatment of diabetes and epilepsy, so this combination therapy is expected to fast for clinical use.They believe that clinical trials should be preferred as having received chemotherapy or radiotherapy, and has appeared elevated prostate-specific antigen in patients with symptoms, followed by further promotion.
According to the French association of urology figures provided by the French ,every year 5 million people are suffering from prostate cancer, 1 million people died of this cancer.